With the abuse.ch FastFlux Tracker you are able to track FastFlux bots in real time. The collected data flows directly in to the drone.abuse.ch DNSBL service. You can use this DNSBL eg. on your email Gateway to reject spammy emails.
Fast-Flux is a technic used by spammer and malware authors to prevent their spammy site to get shutdown. The goal of FastFlux is, to have multiple (hundreds or even thousands) IP addresses assigned to a (spammy, malware, phishing or scam related) domain.